Director Toxicology

Job Description

We are looking for a highly qualified Director of Toxicology to join Jazz Pharmaceuticals, a global biopharmaceutical company dedicated to developing life-changing medicines for patients with serious diseases. As the Director, Toxicology, you will be responsible for managing the global nonclinical regulatory and investigative toxicology of Jazz portfolio products. You will collaborate with cross-functional teams to support the overall global nonclinical regulatory strategy from research to registration and beyond. Reporting to the Head of Toxicology, you will lead, support, and manage direct reports, design and conduct toxicology studies, and prepare regulatory documents to ensure compliance.

Responsibilities

• Lead and manage direct reports in toxicology studies.
• Design, conduct, and monitor toxicology studies at external CROs.
• Interpret and report toxicology findings and prepare regulatory documents.
• Provide toxicology expertise in cross-functional teams supporting drug development programs.
• Ensure compliance with global regulatory requirements.

Requirements

• Ph.D. in Toxicology, Pharmacology, Pathology, Biochemistry, or Biology.
• 8-10 years of experience in small and large molecules, preferably in oncology and CNS indications.
• Experience in authoring non-clinical elements of regulatory submissions.
• Strong knowledge of FDA, EMA, and ICH guidance documents and GLP regulations.
• Excellent communication and scientific writing skills.

Benefits

• Competitive salary range: $192,000-$288,000.
• Annual cash bonus or incentive compensation.
• Equity grants and competitive benefits package.
• Career development opportunities in a global company.